first_imgArchaeological monuments at coastal locations such as those at Kilbarron Castle near Ballyshannon are particularly vulnerable during strong winds and high tides.Recent storms and coastal erosion may have caused damage to County Donegal’s archaeological heritage. The National Monuments Service of the Department of Arts, Heritage & the Gaeltacht is interested in hearing of any damage to archaeological monuments in County Donegal as a result of recent storms and high tides.“Some of our archaeological monuments in coastal locations are particularly vulnerable during storm conditions,” explained Joseph Gallagher, County Donegal Heritage Officer. “The recent combination of strong winds and high tides may have accelerated coastal erosion in the vicinity of archaeological monuments, undermined them, caused collapse or even uncovered archaeological structures or objects.“The National Monument Service of the Department of Arts, Heritage & the Gaeltacht is the statutory organisation charged with ensuring the protection of our archaeological heritage and is keen to hear of any recent damage caused to our archaeological monuments.”As of September 2013, there were 3,396 known archaeological monuments in County Donegal and most of them are in private ownership.Most of these archaeological monuments date from prior to 1700 and all are protected under the National Monuments Acts (1930-2004). Archaeological monuments in coastal locations in County Donegal include promontory forts, castles, tower houses, historic graveyards and holy wells. If you would like to find out what archaeological monuments are on your property, are in your guardianship or are in your area, you can search by townland, town or type of monument on the National Monuments Service website at: Some of these are also identified on the Ordnance Survey Discovery Series maps.If you have any information on damage to archaeological monuments in County Donegal, please contact the County Donegal Heritage Office on (074) 917 2576 / or the Donegal County Museum on (074) 912 4613 / with details as soon as possible.This information will be passed on to the National Monuments Service of the Department of Arts, Heritage & the Gaeltacht. If you would like to find out more about our archaeological heritage, a free brochure entitled ‘Earthen Banks and Broken Walls: our legacy of ancient monuments’ produced by the Department of Arts, Heritage & the Gaeltacht outlining some of the main types of archaeological monuments is available free-of-charge from the County Donegal Heritage Office, Donegal County Council on (074) 917 2576 or by e-mail at: COUNCIL SEEKS INFORMATION ON DAMAGE CAUSED TO DONEGAL’S ARCHEOLOGICAL SITES was last modified: February 4th, 2014 by StephenShare this:Click to share on Facebook (Opens in new window)Click to share on Twitter (Opens in new window)Click to share on LinkedIn (Opens in new window)Click to share on Reddit (Opens in new window)Click to share on Pocket (Opens in new window)Click to share on Telegram (Opens in new window)Click to share on WhatsApp (Opens in new window)Click to share on Skype (Opens in new window)Click to print (Opens in new window)last_img read more

Partial lunar eclipse to be visible over Ireland

first_imgA partial lunar eclipse could be visible from Ireland this Tuesday night on the 50 year anniversary of the first Moon Landing.Two-thirds of the moon will be cast in shadow when the Earth crosses between the sun and moon.Parts of the moon will turn a copper colour during the event, which is expected to be visible from Ireland between 10pm and midnight. Visibility will depending on cloud cover, but stargazers are advised to check the sky for the historic event. According to Astronomy Ireland, the best views will be just as the sky darkens and the moon rises.The eclipse falls on the 50th anniversary of the launch of Apollo 11 from Florida – which took the first men to the moon.The next partial lunar eclipse is not expected until 19 November 2021.Partial lunar eclipse to be visible over Ireland was last modified: July 16th, 2019 by Rachel McLaughlinShare this:Click to share on Facebook (Opens in new window)Click to share on Twitter (Opens in new window)Click to share on LinkedIn (Opens in new window)Click to share on Reddit (Opens in new window)Click to share on Pocket (Opens in new window)Click to share on Telegram (Opens in new window)Click to share on WhatsApp (Opens in new window)Click to share on Skype (Opens in new window)Click to print (Opens in new window) Tags:partial lunar eclipselast_img read more

Genetics “Central Dogma” Is Dead

first_img“The gene is dead… long live the gene,” announced subtitles to an article in Science News this week.1  Geneticists have come to a striking conclusion over the last few years: genes are not the most important things in DNA, if they even exist as a concept.    The “central dogma” of genetics, since Watson and Crick determined the structure of DNA, is that genetic information flows one-way – from the gene to the protein.  In the textbooks, a gene was supposed to be a finite stretch of DNA that, when read by the translation process, produced a messenger RNA, which recruited transfer RNAs to assemble the amino acids for one protein.    As Patrick Barry described in his article “Genome 2.0,”1 the situation in real cells is much messier.  “Mountains of new data are challenging old views,” his subtitle announced, including the “modern orthodoxy” that only genes are important.Researchers slowly realized, however, that genes occupy only about 1.5 percent of the genome.  The other 98.5 percent, dubbed “junk DNA,“ was regarded as useless scraps left over from billions of years of random genetic mutations.  As geneticists’ knowledge progressed, this basic picture remained largely unquestioned….    Closer examination of the full human genome is now causing scientists to return to some questions they thought they had settled.  For one, they’re revisiting the very notion of what a gene is.Some of the findings in the genomic era include:The human genome has far fewer genes than expected.Some lower animals have as many genes as humans (e.g., 05/01/2007).Most of the human genome does not code for genes.The code for proteins can be split between distant parts of the genome – even on different chromosomes.2The non-coding DNA, once considered evolutionary junk (06/15/2007), is actually heavily involved in gene regulation (04/24/2007).Genetic information processing acts more like a network than a static library of genes.RNA transcripts vastly outnumber gene transcripts: some 74 to 93% of the genome.RNA is much more than a messenger in the cell. Numerous small and micro RNA transcripts are heavily involved in “fine tuning” the production of protein.Gene regulation appears more important than the genes themselves.Scientists “are finding disease-associated mutations in regions of the genome formerly regarded as junk.”Some genes overlap with codes for micro-RNAs or regulatory elements.Genes can be read in multiple ways that can yield far more than one protein (alternative splicing; see 05/20/2007)).Messenger-RNA transcripts undergo significant modification and regulation in the nucleus.The translation process can even yield transcripts from the opposing strand.3It remains indisputable that DNA codes for proteins via messenger RNA, and that proteins perform the major structural and functional operations of the cell.  But as Hui Ge of the Whitehead Institute in Cambridge, Massachusetts said, “What we thought was important before was really just the tip of the iceberg.”  Barry used a homey analogy to illustrate how gene regulation can be more important than genes themselves:Consider the difference between a one-bedroom bungalow and an ornate, three-story McMansion.  Both are made from roughly the same materials—lumber, drywall, wiring, plumbing—and are put together with the same tools—hammers, saws, nails, and screws.  What makes the mansion more complex is the way that its construction is orchestrated by rules that specify when and where each tool and material must be used.    In cells, regulation controls when and where proteins spring into action.  If the traditional genome is a set of blueprints for an organism, RNA regulatory networks are the assembly instructions. In fact, some scientists think that these additional layers of complexity in genome regulation could be the answer to a long-standing puzzle……that puzzle being the unexpected low number of genes in the human genome.  It might explain the physical differences between humans and roundworms, which both have similar numbers of protein-coding genes.    Barry’s article provides a good summary of numerous papers that have been casting serious doubt on the Central Dogma, and even the concept of a gene itself:More fundamentally, it muddies scientists’ conception of just what constitutes a gene.  In the established definition, a gene is a discrete region of DNA that produces a single, identifiable protein in a cell.  But the functioning of a protein often depends on a host of RNAs that control its activity.  If a stretch of DNA known to be a protein-coding gene also produces regulatory RNAs essential for several other genes, is it somehow a part of all those other genes as well?Some scientists are advocating changing our focus from genes to “functional RNA transcripts.”  But that seems to just relocate the problem.  If DNA is a passive code, what codes for its activity?  If gene regulation by a network of transcripts is now more important than genes, what regulates the regulators?  Come back for Genome 3.0.Update 09/24/2007:  Colin Nickerson wrote an article for the Boston News that captures the drama of these discoveries:The science of life is undergoing changes so jolting that even its top researchers are feeling something akin to shell-shock.  Just four years after scientists finished mapping the human genome – the full sequence of 3 billion DNA “letters” folded within every cell – they find themselves confronted by a biological jungle deeper, denser, and more difficult to penetrate than anyone imagined….    ….the picture now emerging is more complicated, one in which illness, health, and evolutionary change appear to be the work of almost fantastical coordination between genes and swaths of DNA previously written off as junk.Nickerson quotes Isodore Rigoutsos, geneticist, saying “The picture that’s emerging is so immensely more complicated than anyone imagined, it’s almost depressing.”1Patrick Barry, “Genome 2.0,” Science News, Week of Sept. 8, 2007; Vol. 172, No. 10 , p. 154.2“The ENCODE project revealed that about 90 percent of protein-coding genes possessed previously unknown coding fragments that were located far from the main gene, sometimes on other chromosomes.”3“According to the ENCODE project results, up to 72 percent of known genes have transcripts on the facing DNA strand as well as the main strand.”Many previous entries have dealt with these subjects (e.g., 06/15/2007, 12/29/2006 bullet 2, 11/09/2006, 07/06/2006).  This is a classic case of a paradigm change in science occurring before our eyes.  Even what we mean by an intuitively-obvious word like gene is being questioned: is there such a thing?  Does it have physical reality, or is it a mental picture humans have imposed on a much more subtle reality?  The new buzzword is network, but is that an accurate characterization?  Networking is concerned more with the interactions of entities than with the entities themselves; this means that the rules of the game are more important than the nodes of the network.  How could that fit within a materialistic world view?    Whatever comes in the days ahead, it appears that there is far more information processing occurring in the cell than even Watson and Crick imagined – and that was startling and elegant enough.  Barry states that the raw genetic information transcribed in DNA now appears to be 62 times what genes alone would produce.  The fundamental operational unit of life may, therefore, be nonphysical: information, not molecules.  These are exciting times for science – troubling times for Darwinists.  Don’t expect them to have any remorse over leading mankind into a “modern orthodoxy” that was mistaken.(Visited 72 times, 1 visits today)FacebookTwitterPinterestSave分享0last_img read more

Moz port to boost SA exports

first_img26 April 2007A US$4-million expansion of the ferrochrome terminal at the port of Maputo in Mozambique is currently under way, aimed at increasing exports of the alloy from South Africa.According to the Maputo Port Development Company’s commercial director, Dick Moore, construction on the terminal will be completed in June and the facility will be operational by the end of July.“The bigger ferrochrome terminal will boost ferrochrome exports to more than one million tons per annum over the next few years, so we are very pleased,” Moore said.Ferrochrome, a corrosion-resistant alloy of chrome and iron, is used to produce stainless steel. In South Africa it is mined in Middelburg in Mpumalanga province and Rustenburg in North West province.“The original terminal at Maputo Port was commissioned less than two years ago and was already operating close to capacity,” said Maputo Corridor Logistics Initiative (MCLI) chief executive Brenda Horne.“The terminal handled more than 500 000 tons in 2006, which was mainly shipped to the steel mills of Northern Europe, Japan and China,” Horne added.The MCLI aims to improve infrastructure such as the road and rail link between South Africa and Mozambique as part of the Maputo Development Corridor initiative. It has already resulted in the construction of the R2-billion N4 toll road between Johannesburg and Maputo, as well as linked rail and communication upgrades.The Maputo Port Development Company has a 25-year concession from the Mozambican government to operate Port Maputo.South Africa’s Industrial Development Corporation has been the primary catalyst for SA investment in Mozambique.In March, the IDC has approved funding for 10 projects across Mozambique, and is currently investigating six additional projects in the country. The projects range from mining and mineral beneficiation to agriculture, tourism, chemicals, forestry, transport and energy.Source: BuaNewslast_img read more

Activating Your Ever Present Abilities

first_img Essential Reading! Get my 3rd book: Eat Their Lunch “The first ever playbook for B2B salespeople on how to win clients and customers who are already being serviced by your competition.” Buy Now The attributes you see and admire in other people are always available to you. They are ever present, waiting for you, whenever you decide to activate and deploy them for your benefit, and for the benefit of others.Attitude: The ability to choose an optimistic, empowered attitude is available to you right now. The fact that you are capable of producing this state sometimes is evidence that it is available to you at all times. If I told you that you just won the Powerball, you would immediately find yourself in this state, regardless of any other external events. You can choose that state now.Beliefs: The ability to change your beliefs is ever present. You can change your mind about something anytime you want to. At some point in time, you shed your childish beliefs. You still hold beliefs that no longer serve you, and some that never really did. You can change those beliefs as soon as you become aware of them and bravely embrace something new.Meaning: At any time, you can change the frame you use to define what something means. You can switch from a negative frame to a positive frame. You might frame up the circumstances of your birth as negative, using that as an explanation for why things are the way they are now. Someone else believes that story is their origin story and they use it to explain why they are successful now.Focus: You have the ability to give your full and undivided attention to someone or something. The ability to block out the infinite distractions that vie for your limited time and attention is wholly within your control. Whenever you decide that something is important enough to do it with impeccable care, you can focus and make it so.Act: You can do something. What you do may or may not work, but you can always take some action. Most everything is outside of your control, but you have the ability to control yourself and your actions. That’s all you have, and that is enough.Not Act: The ability to not act is ever present too. Much of what captures your attention isn’t worth your attention. You don’t have to respond physically or emotionally to any external stimulus. You can do nothing.Compassion: You can exercise compassion. The ability to assume others are acting out of good intentions is a super power when it comes to maintaining a positive, optimistic outlook. You can forgive, and you can help those who need help.None of these choices is forbidden you. You were born with access to all of them. All that is left for you to do is to decide.last_img read more